Radiology Search - The Right Place for Searching Radiology Information ... A Radiology search engine developed for Radiologists by Radiologists ...
...the most exciting new development in modernized patient care...(read more)
Search Radiology contents from thousands of peer reviewed Radiology websites and hundreds of Radiology journals!



Include: Semantic search :: Video search :: Quick image search
My Search :: About :: What's new :: Forum :: Online Tutorial :: Feedback :: Contact Us :: Home


Bookmark and Share

Published: . Dec 2014


McCarville MB, Muzzafar S, Kao SC, Coffin CM, Parham DM, Anderson JR, Spunt SL

Imaging features of alveolar soft-part sarcoma: a report from Children's Oncology Group Study ARST0332.
(AJR Am J Roentgenol)

There are few studies in the literature regarding the imaging features of alveolar soft-part sarcoma (ASPS). We performed a comprehensive assessment of the imaging characteristics of this rare tumor to determine whether there are features that suggest the diagnosis. Twenty-two subjects with ASPS underwent pretherapy imaging as part of enrollment in Children's Oncology Group protocol ARST0332 for the treatment of nonrhabdomyosarcoma soft-tissue sarcomas: 16 patients underwent MRI; three, CT; and three, both MRI and CT. Two radiologists retrospectively reviewed the imaging studies by consensus and recorded tumor location, size, contour, internal architecture, signal characteristics, presence of flow voids, and enhancement patterns. The 12 females and 10 males in the study group ranged in age from 8 to 23 years 7 months (mean, 15 years 8 months). The most common anatomic site was the lower extremity (12/22, 55%) followed by the upper extremity (4/22, 18%). The maximal tumor diameter ranged from 2.3 to 20.0 cm (median, 5.9 cm). All tumors imaged with MRI had flow voids (19/19, 100%), and 19 (19/22, 86%) had large peripheral vessels, lobulated margins, and nodular internal architecture. Unenhanced T1-weighted MRI was available for 18 tumors: 14 (14/18, 78%) appeared slightly hyperintense to muscle. Of the 16 tumors imaged with contrast material, 11 (11/16, 69%) showed intense enhancement and five (5/16, 31%), moderate enhancement. Six tumors (6/16, 38%) had a thick enhancing peripheral rim with a nonenhancing center consistent with necrosis. The imaging features of ASPS include flow voids, large peripheral vessels, internal nodularity, and lobulated margins. Contrast administration produces intense to moderate enhancement, sometimes with a thick enhancing peripheral rim around central necrosis. Extremity tumors with these imaging features in a child or young adult should suggest the diagnosis of ASPS.

-> Read fulltext

Read more articles from the authors:
1. McCarville MB
2. Muzzafar S
3. Kao SC
4. Coffin CM
5. Parham DM
6. Anderson JR
7. Spunt SL


Related articles

Read abstract in PubMed

Do search in PubMed

Copy citation:

Export to Bibtex
Export to EndNote
Export to Reference Manager



Bookmark and Share

Add to Yahoo    Add to Del.icio.us    Add to Google    Add to AOL    Add to Furl    Add to Connotea    Add to Citeulike    Add to Stumbleupon    Add to Dissect medicine    Add to 2collab   

Add Radiology Search to your search engines :: Put Radiology Search on your website :: Make Radiology Search your homepage :: Add Radiology Search to your favorites
© 2017 Radiology Search